Enabling High Precision In Vivo CAR-T Therapy with Targeted Fusogens
Time: 1:45 pm
day: Day One
Details:
- Comparing methods of cell specific in vivo CAR-T generation.
- Enabling high precision cell-specific gene editing with Sana’s Fusogen platform, which mediates cell entry via a mechanism that directly couples receptor recognition to cell entry, in contrast to endosomal escape delivery systems.
- Developing a T cell-specific Fusogen to enable in vivo CAR-T therapy, including in vivo data showing potent and cell-specific CAR-T generation and robust B cell depletion in animal models.
