Novel CRISPR-Associated Gene-Editing Systems from Metagenomic Samples Enable Efficient & Specific Genome Engineering In Vivo

Time: 3:30 pm
day: Day Two


• Assembly and interrogation of a metagenomic database reveals new gene-editing systems with attractive properties
• Metagenomi nucleases can be used to create a wide variety of engineered primary immune cells
• Metagenomi nucleases effect extremely efficient gene editing in the mouse liver